| 摘要: |
| 目的 采用超声心动图评价肺动脉压正常的慢性肝病患者(CLD)右心形态和功能的变化。方法 纳入102例肺动脉压正常的CLD患者(研究组),并纳入50例年龄和性别与研究组匹配的受试者作为对照组。采用超声心动图评价其右心室(RV)和右心房(RA)大小、RV收缩/舒张功能指标以及心肌应变。结果 与对照组比较,CLD患者的RV和RA大小、RV收缩/舒张功能指标以及心肌应变表现相似(P >0.05),而CLD患者的RV游离壁厚度对于对照组(P <0.05)。CLD患者RV舒张末期直径和RA面积与RV游离壁厚度呈正相关(P <0.05)。结论 对于肺动脉压正常的CLD患者而言,其RV游离壁的厚度可能增加。然而,在没有肺动脉高压的情况下,肝硬化性心肌病可能不会导致其RV收缩或舒张功能的受损。 |
| 关键词: 超声心动描记术 右心室 右心房 慢性肝病 肺动脉高压 |
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| 基金项目:四川省卫生和计划生育委员会课题(150107)。 |
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| Evaluation of the right heart in patients with chronic liver disease and normal pulmonary artery pressure: an echocardiographic study |
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| Abstract: |
| Objective To evaluate the morphologic and functional changes of the right heart in patients with chronic liver disease (CLD) and normal pulmonary artery. Methods One hundred and two subjects (study group) with CLD and normal pulmonary artery were included, along with fifty age- and sex-matched participants as the control group. Right ventricular (RV) and right atrial (RA) dimensions, indices of RV systolic/diastolic function, and myocardial strain were measured by standard echocardiographic studies. Results When compared with control study, patients in the study group had similar RV and RA dimensions, indices of RV systolic/diastolic function and the strain imaging findings (P >0.05). However, the RV free wall thickness was significantly higher in the study group (P <0.05). RV end-diastolic diameter and RA area had a significant correlation with RV free wall thickness in patients with CLD. Conclusions Increased RV free wall thickness maybe identified in patients with CLD and normal systolic pulmonary pressure. However, in the absence of pulmonary hypertension, cirrhotic cardiomyopathy may not cause impaired RV systolic or diastolic function. |
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