| 摘要: |
| 目的：探究使用美罗培南后发生的AST、ALT、ALP值升高是否与性别，年龄，用药疗程之间是否有关系。 方法：对某院使用过注射用美罗培南药物的住院病人进行分析，将AST、ALT、ALP升高的患者数分别对其性别，年龄，用药疗程进行卡方分析，考察它们相关性是否具有统计学意义。结果：111名纳入研究范围，其中共有11名患者（占总人数的9.91%）出现AST升高，9名患者（占总人数的8.11%）出现ALT升高，有10名患者（占总人数的9.01%）出现ALP升高。三种转氨酶分别对性别、年龄、用药疗程进行卡方分析，其P值均大于0.05。结论：使用美罗培南后AST、ALT、ALP的升高与性别、年龄和用药疗程无相关性。 |
| 关键词: 美罗培南 转氨酶升高 相关因素 卡方分析 |
| DOI： |
| 分类号: |
| 基金项目: |
|
| Analysis of the related factors of AST.ALT.ALP elevation in patients with meropenem |
|
|
|
|
| Abstract: |
| Abstract：Objective: In order to explore whether the increase in AST，ALT， and ALP values after the use of meropenem was associated with gender, age, and course of treatment. Methods: The inpatients who used meropenem for injection in a hospital were analyzed. The number of patients with elevated AST, ALT and ALP were analyzed by chi-square method for their gender, age and course of treatment, and the correlation between them was investigated. Results: 111 patients were included in the study. Among them, 11 patients (9.91% of the total) had elevated AST, 9 patients (8.11% of the total) had elevated ALT, and 10 patients (9.01% of the total) had elevated ALP. Chi-square analysis on sex, age and treatment course showed that all the P values were greater than 0.05. Conclusion: The elevation of AST, ALT and ALP after meropenem administration was not correlated with sex, age and course of treatment. |
| Key words: meropenem Transaminase elevation Relevant factors Chi-square analysis |