摘要: |
目的探讨骨髓增生性疾病发生缺血性脑卒中的临床和影像特点。方法回顾性分析2015年至2016年在我院和绵阳市中心医院住院的39例骨髓增生性疾病所致的缺血性脑卒中患者,分析病例的临床表现、生化检查、头颅MRI表现、治疗方法和预后。结果 39例患者中,10例为白细胞、红细胞和血小板三系增高(25%),4例为红细胞和血小板增高(10%),6例为白细胞和血小板增高(15%),19例为血小板增高(50%);头颅MRI提示病灶为额顶叶、枕叶10例(26%)、基底节6例(20%),大面积脑梗死4例(10%),枕叶2例(13%),多发性腔隙性梗死10例(26%),小脑半球5例(15%),静脉窦血栓形成2例(5%)。39例均行病因学干预治疗,其中37例(95%)药物干预,2例(5%)离开高原环境、控制血糖血脂后恢复正常。结论要重视脑梗塞病因的收集,对骨髓增生性疾病的特殊病因进行干预,更有利于脑梗死的恢复和防复发。 |
关键词: 骨髓增生性疾病 缺血性脑卒中 头颅MRI 病因治疗 |
DOI: |
分类号: |
基金项目:四川省卫计委科研项目(编号:16PJ060) |
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Clinical and Imaging Features of Myeloproliferative Disorders Complicated with Ischemic Stroke |
Wu Xiaoping;Zhang Yun;Rao Ping1,2
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1.Neurology Department,The First People’s Hospital of Chengdu;2.Mianyang Central Hospital
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Abstract: |
Objective To investigate the clinical and imaging features of ischemic stroke caused by myeloproliferative disorders.Methods A retrospective analysis of 39 patients with ischemic stroke caused by myeloproliferative diseases from 2015 to2016 in our hospital and Mianyang Central Hospital was carried out. The clinical manifestations,biochemical examination,cranial MRI findings,treatment methods and prognosis of the patients were analyzed.Results In the 39 cases of patients,10 cases of increase of white blood cells,red blood cells and platelets( 25%),4 cases of increase of red blood cells and platelets( 10%),6 cases of increase of white blood cells and platelets( 15%),and 19 cases of increase of thrombocytosis( 50%); Cranial MRI showed that the lesions were frontal parietal lobe and occipita lobe in 10 cases( 26%),basal ganglia in 6 cases( 20%),large area cerebral infarction in 4 cases( 10%),occipital lobe in 2 cases( 13%),multiple lacunar infarction in 10 cases( 26%),cerebellar hemisphere in 5 cases( 15%),and venous sinus thrombosis in 2 cases( 5%).39 cases were all treated with etiological intervention,including 37 cases( 95%) of drug intervention,2 cases( 5%) returned to normal after they left the plateau environment,and the blood sugar and blood lipids were controlled.Conclusion Attention should be paid to the collection of causes of cerebral infarction. And intervention of the special causes of myeloproliferative diseases will be more effective in the recovery and prevention of recurrence of cerebral infarc |
Key words: myeloproliferativedisorders ischemicstroke headMRI etiologicaltreatment |