| 摘要: |
| 目的探讨鼻息肉组织中的嗜酸性粒细胞浸润程度与手术预后的关系,以及与外周血嗜酸性粒细胞计数的关系。方法回顾性研究77例诊断为慢性鼻窦炎伴有鼻息肉的患者,根据术后鼻息肉组织中嗜酸性粒细胞浸润程度,将其分为嗜酸性粒细胞组和非嗜酸性粒细胞组,比较两组患者的外周血嗜酸性粒细胞计数以及两组患者术后6个月随访复查患者的治疗效果有无统计学差异。结果嗜酸性粒细胞组和非嗜酸性粒细胞组两组患者在治疗效果的差异具有统计学意义,但两组患者的外周血嗜酸性粒细胞计数结果无统计学差异。结论鼻息肉组织中嗜酸性粒细胞浸润型患者较非嗜酸性粒细胞型患者手术治疗效果差,易复发,鼻息肉组织中嗜酸性粒细胞浸润情况可作为判断术后疗效的一项重要指标。 |
| 关键词: 慢性鼻-鼻窦炎 嗜酸性粒细胞 鼻息肉 |
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| Study on the Relationship Between Infiltration Degree of Eosinophils in Nasal Polyp Tissues and Prognosis of Surgery |
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Chen Wei;Mao Yu;Qiu Changming
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Department of Otorhinolaryngology and Department of Pathology,Leshan People’s Hospital
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| Abstract: |
| Objective To investigate the relationship between the infiltration degree of eosinophils in nasal polyp tissues and the prognosis of surgery,and its relationship with eosinophil count in peripheral blood. Methods 77 cases of patients diagnosed as chronic rhinosinusitis with nasal polyps were retrospectively studied and divided into eosinophil group and non-eosinophil group according to postoperative eosinophil infiltration degree in nasal polyp tissues.The eosinophil counts in peripheral blood and the therapeutic effect of the patients in the two groups at their follow-up and re-examination 6 months after operation,were compared.Results The difference of therapeutic effect between eosinophil group and non-eosinophil group was statistically significant,but the difference of eosinophil counts in peripheral blood between the groups was not statistically significant.Conclusion Patients with eosinophil infiltration in nasal polyps has worse therapeutic effect of surgery than patients without eosinophil infiltration in nasal polyps,easy to relapse.The infiltration of eosinophils in nasal polyps can serve as an important indicator for judging the postoperative curative effect |
| Key words: chronicrhinosinusitis eosinophil nasalpolyp |
