摘要: |
目的探讨多囊卵巢综合征(polycystic ovary syndrome,PCOS)中代谢综合征(metabolic syndrome,MS)的患病情况以及各项检测指标与MS患病的相关性,以利于早期筛查及干预。方法初次确诊的PCOS患者121例,年龄20~39岁,测量身高、体重、腰围(WC)、血压、体脂肪含量(BF%)、血糖(FPG)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、胰岛素(FINS)、睾酮(T)。并计算体质量指数(BMI)及胰岛素抵抗指数(HOMA-IR),分析检验结果。结果 121例PCOS患者,平均年龄(29.88±5.56)岁,平均BMI(26.06±3.75)kg/m2;其中符合MS诊断者25.62%。按每5岁为一个年龄组比较,随着年龄增加,MS的发生率增加;30~34岁组和35~39岁明显高于其他两组(P<0.05)。合并MS组的年龄、WC、BMI、BF、收缩压、TG、TG/HDL-C、FINS、HOMA-IR均高于非MS组(P<0.05);HDL-C低于非MS组(P<0.05);两组舒张压、FPG比较无统计学差异(P>0.05);所有PCOS患者各项异常发生率在26.44%~63.63%。WC、HDL-C及FPG异常发生率明显高于其他指标,结果有统计学意义(P<0.05)。结论随着年龄、WC、BF、TG/HDL-C增加PCOS患者的MS发生率明显增加;所有指标中WC结合HDL-C及FPG可能最有利于筛查PCOS中合并MS的患者;临床中可考虑将上述简便指标结合起来对PCOS患者进行评估,有利于早期发现潜在的MS风险和早期干预,以预防PCOS的远期并发症。 |
关键词: 多囊卵巢综合征 代谢综合征 腰围 |
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Analysis of Related Factors of Polycystic Ovary Syndrome and Metabolic Syndrome |
Zhang Jing;Huang Wei1,2
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1.West China Second Hospital,Sichuan university;2.Chengdu Women and Children Center Hospital
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Abstract: |
Objective To investigate the polycystic ovary syndrome( PCOS) in metabolic syndrome( MS) in the prevalence and correlation between indexes and MS,in order to facilitate the early screening and intervention. Methods 121 cases of patients with PCOS,aged 20 to 39,measure the height,weight,waist circumference( WC),blood pressure,body fat( BF %),blood glucose( FPG),triglycerides( TG),high-density lipoprotein( HDL-C),insulin( FINS),testosterone( T). The body mass index( BMI) and the insulin resistance index( homa-ir) were detected and analyzed.Results 121 cases of PCOS,Average age( 29.88±5.56),the average BMI of( 26.06±3.75) kg/m2; But 25.62% diagnosed with MS. Per for a five years old age group,with the increase of age,the incidence of MS increases; 30 ~ 34 group and 35 to 39,significantly higher than the other two groups( P<0.05).Increase With age MS,WC,BMI,BF,systolic blood pressure,TG,TG/HDL-C and HOMA-IR were higher than those in non MS group( P<0.05); HDL-C lower than non MS group( P<0.05); group two,FPG diastolic blood pressure had no significant difference( P>0.05); all the abnormal rate in PCOS patients 26.44 ~ 63.63%. The incidence of WC,HDL-C and FPG abnormalities was significantly higher than other indicators,the results were statistically significant( P<0.05). Conclusion With age,WC,BF,TG/HDL-C increased in the patients of PCOS,the cases of MS significantly increased.In the all indexes,the combination of WC,HDL-C and FPG may be the most conducive to the screening of PCOS in patients with MS.In clinical practice,PCOS patients were evaluated by the simple index that is conducive to the early detection of potential MS risk and early intervention,in order to prevent long-term complications of PCOS. |
Key words: polycysticovarysyndrome metabolicsyndrome waistcircumference |