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DWI在宫颈癌诊断及治疗疗效评估中的应用价值分析
朱峰正; 朱林; 黄阳光; 梁玲俐; 蔡锦杏
南方医科大学附属小榄医院放射科
摘要:
目的探讨磁共振弥散加权成像(DWI)技术应用于宫颈癌的诊断及治疗效果评估中的价值。方法选取我院收治的宫颈癌患者60例(病例组),收集时间2015年6月至2017年1月,同期宫颈检查正常的妇女30例(对照组),采用DWI技术检测两组妇女并比较ADC值,并根据病理学检查结果分层分析不同宫颈癌特征患者的ADC值,对比治疗前后不同临床疗效患者的ADC值。结果病例组宫颈组织的ADC值显著的低于对照组,差异有统计学意义(P<0.05);宫颈鳞癌与腺癌患者的ADC值比较,差异无统计学意义(P>0.05);FIGO分期为Ⅰ期、Ⅱ期的宫颈癌患者与Ⅲ期、Ⅳ期的宫颈癌患者的ADC值比较,差异无统计学意义(P>0.05);不同分化程度的宫颈癌患者ADC组间比较差异有统计学意义(P<0.05),随着分化程度的降低,ADC值越来越小;经过治疗,共获得CR患者14例、PR患者28例、SD患者15例、PD患者3例;治疗后,CR+PR患者的ADC值显著的高于SD+PD患者,差异有统计学意义(P<0.05)。结论 DWI技术应用于宫颈癌的诊断及治疗效果评估具有重要的临床实用价值。
关键词:  磁共振弥散加权成像  宫颈癌  治疗效果  诊断
DOI:
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基金项目:中山市医学科研项目(编号:2017A020290)
Analysis of the Value of DWI in the Diagnosis and Treatment of Cervical Cancer
Zhu Fengzheng;Zhu Lin;Huang Yangguang
Department of Radiology,Xiaolan Hospital Affiliated to Southern Medical University
Abstract:
Objective To evaluate the value of diffusion-weighted MR imaging( DWI) in the diagnosis and treatment of cervical cancer.Methods 60 cases of cervical cancer patients treated in our hospital from June 2015 to January 2017 were selected as the case group,and 30 women with normal cervical examination at the same time were selected as the control group. DWI was used to detect the two groups of women and compare the ADC value,and according to the pathological examination results,stratified analysis of ADC value in patients with different cervical cancer characteristics were carried out,and the ADC values of patients with different clinical effects before and after treatment were compared.Results The ADC value of cervical tissue in the case group was significantly lower than that in the control group,and the difference was statistically significant( P<0. 05); There was no significant difference in ADC value between cervical squamous cell carcinoma and adenocarcinoma( P>0. 05); There was no significant difference in the ADC value between patients withstageⅠand stage II cervical cancer and patients with stage III and stage IV cervical cancer in FIGO staging( P>0. 05); There were significant differences in ADC value between the groups with different differentiation degree( P<0. 05),with the decrease of differentiation,the ADC value was getting smaller and smaller; After treatment,14 cases of CR patients,28 cases of PR,15 cases of SD,and 3 cases of PD were obtained; After treatment,the ADC value of patients with CR+PR was significantly higher than that of patients with SD +PD,and the difference was statistically significant( P< 0. 05). Conclusion The application of DWI technique in the diagnosis and treatment evaluation of cervical cancer has important clinical practical value
Key words:  magneticresonancediffusionweightedimaging  cervicalcancer  treatmenteffect  diagnosis
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