| 摘要: |
| 目的 研究RhCcEe抗原配合性悬浮红细胞输注对提高温抗体型自身免疫性溶血性贫血(AIHA)患者紧急输血安全性和有效性的作用。方法 根据输血情况将我院温抗体型AIHA患者接受紧急红细胞血液成分输注者分为A、B、C三组,A组进行ABO,Rh C、c、D、E、e抗原相合性或相容性悬浮红细胞输注;B组仅进行ABO、RhD相合性悬浮红细胞输注;C组进行ABO、RhD相合性洗涤红细胞输注。观察三组研究对象血液输注的有效性,溶血情况的改变及输血不良反应发生情况。结果 ①输注有效例数比率A组>B组、C组,差异有统计学意义(P<0.05);②三组治疗后网织红细胞、胆红素、血红蛋白(Hb)与同组治疗前对比,差异有统计学意义(P<0.05);③治疗后网织红细胞、胆红素A组B组、C组,差异有统计学意义(P<0.05);④B组、C组治疗有效性,差异无统计学意义(P>0.05);⑤三组不良反应发生率差异无统计学意义(P>0.05)。结论 ABO、RhCcEe抗原配合性悬浮红细胞输注可提高AIHA紧急情况下输血有效性,并不会增加输血不良反应,因此可以在抗体鉴定有困难的基层医院或不能满足抗体鉴定耗时长的紧急情况输血中使用。 |
| 关键词: Rh血型系统 配合性输血 自身免疫性溶血性贫血 安全性 有效性 |
| DOI：10.16252/j.cnki.issn1004-0501-2021.01.008 |
| 分类号:R457.1 |
| 文章编号:1004-0501(2021)01-0031-04 |
| 文献标识码:A |
| 基金项目: |
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| Application of RhCcEe Antigen Compatibility Management Suspension Erythrocyte in Emergency Blood Transfusion of Patients with Autoimmune Hemolytic Anemia. |
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Wang Yuhan, Wang Hua, Wang Jie, Jiang Ling, Huang Yuanshuai
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Department of Blood Transfusion, The Affiliated Hospital of Southwest Medical University, Luzhou,Sichuan 646000 , China.
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| Abstract: |
| Objective To study the effect of RhCcEe compatibility management on improving the safety and efficiency of blood transfusion in patients with autoimmune hemolytic anemia(AIHA). Methods AIHA patients in our hospital who accepted urgent infusion of erythrocytes were randomly divided into three groups A, B and C. ABO, Rh C, c, D, E, e antigen compatibility transfusion was performed in the group A, only ABO and RhD antigen compatible transfusion was performed in the group B, and ABO and RhD compatible washing erythrocyte transfusion was performed in group C. The effectiveness of blood transfusion, the change of hemolysis index and the occurrence of adverse reactions of blood transfusion in the three groups were observed. Results ① the effective rate of infusion in group A>group B, and group C, P<0.05;② there was a statistically significant difference of reticulocyte, bilirubin and hemoglobin in the three groups and the treatment of the same group between after treatment and before, P<0.05;③ after treatment, reticulocyte, bilirubin A groupgroup B, C group, P<0.05;④there was no statistically significant difference in therapeutic efficacy between group B and group C(P>0.05).⑤ there was no statistically significant difference in the incidence of adverse reactions between the three groups, P>0.05. Conclusion ABO and RhCcEe antigen compatible suspension erythrocyte infusion can improve the effectiveness of blood transfusion in AIHA emergencies and does not increase the adverse reactions of blood transfusion. Therefore, it can be used in primary hospitals with difficulty in antibody identification or in emergency blood transfusion that cannot meet the requirement of time-consuming antibody identification. |
| Key words: Rh blood group system compatibility management autoimmune hemolytic anemia safety efficiency |
