| 摘要: |
| 目的探讨低血糖负荷饮食联合运动对代谢综合征患者的干预效果。方法选取84例代谢综合征患者,随机分为观察组和对照组各42例,对照组采用常规药物治疗,观察组在常规药物治疗的基础上,采取低血糖负荷饮食联合运动的方式进行6个月的干预。采用化学发光法检测6个月前后患者的血清SHBG水平,同时评估6个月前后两组患者的身体质量指数和腹围,对两组患者的空腹血糖(FBG)、甘油三酯(TG)指数以及高密度脂蛋白胆固醇(HDL-C)和总胆固醇(TC)达标情况进行比较分析。结果观察组干预前身体质量指数和平均腹围为(33.5±3.8)kg/m~2和(105.4±4.1)cm,对照组干预前身体质量指数和平均腹围为(34.8±4.3)kg/m~2和(106.1±3.8)cm;6个月后,观察组身体质量指数和平均腹围为(27.6±2.4)kg/m~2和(95.2±4.3)cm,对照组身体质量指数和平均腹围为(31.2±4.6)kg/m~2和(102.8±3.2)cm;两组患者数据比较差异有统计学意义(P<0.05)。观察组和对照组干预前血清SHBG水平分别为(11.5±6.7)nmol/L和(10.5±7.2)nmol/L,6个月后,观察组血清SHBG水平改变为(25.34±17.58)nmol/L,对照组血清SHBG水平改变为(14.9±13.7)nmol/L,两组患者干预前后血清SHBG水平比较差异有统计学意义(P<0.05)。观察组干预前的空腹血糖、甘油三酯指数分别为(6.26±0.58)mmol/L、(2.55±0.76)mmol/L,对照组干预前的空腹血糖、甘油三酯指数分别为(6.12±0.72)mmol/L、(2.58±0.83)mmol/L;观察组干预后的空腹血糖、甘油三酯指数分别为(4.36±0.57)mmol/L、(1.54±0.24)mmol/L,对照组的空腹血糖、甘油三酯指数分别为(5.42±0.48)mmol/L、(2.08±0.62)mmol/L,两组患者数据比较差异有统计学意义(P<0.05)。观察组干预前HDL-C达标4例(9.52%)、TC达标5例(11.90%),对照组干预前HDL-C达标5例(11.90%)、TC达标6例(14.29%);观察组干预后后HDL-C达标23例(54.76%)、TC达标20例(47.62%),对照组干预后HDL-C达标9例(21.43%)、TC达标11例(26.19%);两组患者数据比较差异有统计学意义(P<0.05)。结论低血糖负荷饮食联合运动能够显著提升代谢综合征患者身体质量水平,提高SHBG水平,有效促进代谢综合征患者代谢状态的改善。 |
| 关键词: 低血糖负荷饮食 运动 代谢综合征 |
| DOI： |
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| Intervention Effect of Low Blood Pressure Diet Combined with Exercise on 4atients with Metabolic Syndrome |
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Tang Qi;Hou Bin;Wen Ye
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West China Fourth Hospital
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| Abstract: |
| Objective To investigate the intervention effect of low glycemic stress diet combined with exercise on metabolic syndrome.Methods 84 patients with metabolic syndrome were randomly divided into the observation group and the control group,each with 42 cases.The control group was treated with conventional medicine,and the observation group was treated with hypoglycemic diet and combined exercise for 6 months on the basis of routine drug treatment.Serum SHBG levels were measured by chemiluminescence method before and after 6 months.At the same time the body mass index and waist circumference of patients in the two groups before and after 6 months were assessed.And the fasting blood glucose(FBG),triglyceride(TG) index,and high-density lipoprotein cholesterol(HDL-C) and total cholesterol(TC) levels were compared between the two groups.Results The body mass index and average waist in the observation group before the intervention were(33.5±3.8) kg/m~2and(105.4±4.1) cm,whilethe body mass index and average waist in the control group before the intervention were(34.8±4.3) kg/m~2and(106.1±3.8)cm; After 6 months,the body mass index and average waist in the observation group were(27.6±2.4) kg/m~2and(95.2±4.3) cm,while the body mass index and average waist in the control group were(31.2±4.6) kg/m~2and(102.8±3.2) cm; The difference of data between the two groups was statistically significant(P<0.05).The serum SHBG levels of the observation group and the control group before the intervention were respectively(11.5±6.7) nmol/L and(10.5±7.2) nmol/L; After 6 months,the serum SHBG levelsof the observation group was changedas(25.34±17.58) nmol/L,while the serum SHBG levels of the control group was changed as(14.9±13.7) nmol/L; The difference of serum SHBG levels between the two groups before and after intervention was statistically significant(P< 0.05).The fasting blood glucose and triglyceride index before intervention in the observation group were(6.26 ±0.58) mmol/L、(2.55±0.76) mmol/L,the fasting blood glucose and triglyceride index before intervention in the control group were(6.12±0.72) mmol/L、(2.58±0.83) mmol/L; The fasting blood glucose and triglyceride index after intervention in the observation group were(4.36±0.57) mmol/L、(1.54±0.24) mmol/L,while the fasting blood glucose and triglyceride index after intervention in the control group were(5.42±0.48) mmol/L、(2.08±0.62) mmol/L; The difference of data between the two groups was statistically significant(P<0.05).In the observation groupbefore the intervention,4 cases(9.52%) reached the standard of HDL-C,and 5 cases(11.90%) reached the standard of TC; In the control groupbefore the intervention,5 cases(11.90%) reached the standard of HDL-C before the intervention,and 6(14.29%) reached the standard of TC; In the observation group after the intervention,23 cases(54.76%) reached the standard of HDL-C,20 cases(47.62%) reached the standard of TC,whilein the control group after the intervention,9 cases(21.43%) reached the standard of HDL-C,11 cases(26.19%) reached the standard of TC; The difference of data between the two groups was statistically significant(P < 0.05).Conclusion Low blood pressure diet combined exercise can significantly improve the physical quality of patients with metabolic syndrome,improve the level of SHBG,and effectively promote the metabolic status of patients with metabolic syndrome. |
| Key words: lowglycemicstressdiet exercise metabolicsyndrome |
