| 摘要: |
| 目的探讨迪克乐克与硫酸羟氯喹治疗风湿病的临床效果。方法选取2012年12月至2014年12月我院就诊的168例风湿病患者,随机分为试验组和对照组各84例,对照组采用迪克乐克进行治疗,试验组采用迪克乐克与硫酸羟氯喹联合治疗,治疗1个月,观察两组患者的治疗效果。结果试验组的总有效率(95.2%)明显高于对照组(77.4%),具有统计学意义(X~2=6.895,P<0.05);两组患者治疗后的晨僵、握力、关节肿胀数、关节肿胀指数、关节压痛数和压痛指数等指标明显优于治疗前,具有统计学意义(P<0.05);试验组治疗后的治疗后晨僵、握力、关节肿胀数、关节肿胀指数、关节压痛数和压痛指数等指标明显优于对照组,具有统计学意义(P<0.05);试验组的不良反应发生率(6.0%)明显低于对照组(23.8%),具有统计学意义(X~2=5.855,P<0.05)。结论采用迪克乐克与硫酸羟氯喹治疗风湿病可以有效的改善患者疼痛症状,提高患者的行动能力,安全性好,具有重要的临床意义。 |
| 关键词: 风湿病 迪克乐克 硫酸羟氯喹 临床效果 |
| DOI： |
| 分类号: |
| 基金项目: |
|
| Clinical Observation on the Treatment of Rheumatic Disease with Hydroxychloroquine and Hydroxychloroquine Sulfate |
|
Zhou Ding;
|
|
Panzhihua Central Hospital
|
| Abstract: |
| Objective To investigate the clinical effect of Dikeleke and hydroxychloroquine sulfate in the treatment of rheumatism.Methods 168 cases of rheumatism patients came to our hospital for treatmentfrom December 2012 to December 2014 were selected for analysis of western medicine treatment,randomly divided into experimental group and control group,84 cases each.The control group was treated by Dikeleke,while the experimental group was given combined treatment of Dikeleke and hydroxychloroquine sulfate.After 1 month of treatment,the curative effect of the two groups was observed.Results The total effective rate of the experimental group( 95. 2%) was significantly higher than that of the control group( 77. 4%),with statistical significance(X~2= 6. 895,P<0. 05); Indexes such as morning stiffness,grip strength,joint swelling,joint swelling index,joint tenderness and pain index of the two groups after treatment were obviously better than before treatment,with statistical significance( P<0. 05); Indexes such as morning stiffness,grip strength,joint swelling,joint swelling index,joint tenderness and pain index of the treatment group after treatment were obviously better than those of the control group,with statistical significance( P < 0. 05); The incidence of adverse reactions in the experimental group( 6. 0%) was significantly lower than that of the control group( 23. 8%),with statistical significance(X~2= 5. 855,P<0. 05). Conclusion The use of Dikeleke and hydroxychloroquine sulfate in the treatment of rheumatic disease can effectively improve the patients’ pain symptoms,improve the patient’s ability to act,with good safety,which has important clinical significance. |
| Key words: rheumaticdisease dikeleke hydroxychloroquinesulfate clinicalefficacy |
