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老年精神疾病患者院内感染病原菌的临床特征分析
杨晓丽; 申娟; 刘利君; 马长林1,2
1.上海市嘉定区精神卫生中心医教科老年科精神科;2.上海市嘉定镇社区卫生服务中心中医科
摘要:
目的探讨老年精神疾病患者院内感染病原菌种类及其临床特征。方法选取2015年1月1日至2016年12月31日我院精神科收治的461例老年精神疾病患者作为研究对象,采用系统性回顾法分析所有患者的临床资料,根据资料结果统计所有住院患者中院内感染的发生情况,且通过临床相关检查结果分析感染患者的主要病原菌和其临床特征。结果感染组患者其年龄和住院时间均大于未感染组,BMI小于未感染组,差异有统计学意义(P<0.05)。本组共送检标本140次,分离培养出病原菌8种共25株,阳性检出率17.86%,G+菌9株,占36.00%;G-菌16株,占64.00%,其中最常见病原菌感染为沙门菌志贺菌感染,且G-菌感染较为多见。院内感染大多数(71.43%)为首次感染,且上呼吸道感染(45.71%)最为常见;精神分裂症患者其发生院内感染所占比最高(62.86%),冬季(41.43%)是感染高发季节。多因素分析可得年龄和住院时间为老年精神疾病患者院内感染发生的独立影响因素(P<0.05)。结论导致老年精神疾病患者发生院内感染的主要病原菌为革兰性阴性菌,以呼吸道感染为主,且住院时间及年龄与院内感染发生有着密切联系。
关键词:  老年  精神疾病  院内感染  病原菌  临床特征
DOI:
分类号:
基金项目:上海市嘉定区精神卫生重点专科建设(编号:JDYXZDZK-3);上海市嘉定区精神卫生重点专科建设子课题(编号:ZKT201501)
Clinical Characteristics of Pathogens Causing Nosocomial Infections in Elderly Patients with Mental Disorders
Yang Xiaoli;Shen Juan;Liu Lijun1,2
1.Department of Medical Education,Geriatrics,Psychiatry,Jiading District Mental Health Center in Shanghai;2.Department of Traditional Chinese Medicine,Community Health Service Center,Jiading Town,Shanghai
Abstract:
Objective To investigate the type of pathogens and clinical characteristics of nosocomial infection in elderly patients with mental disorders.Methods 461 elderly patients with mental disorders admitted to the psychiatric department of our hospital from January 1,2015 to December 31 st,2016 were selected as the research objects. The clinical data of all patients were analyzed by systematic review method.According to the results of data,the incidence of nosocomial infection in all hospitalized patients was counted,and the main pathogenic bacteria and clinical characteristics of the infected patients were analyzed by related clinical examination results.Results The age and length of hospital stay in the infection group were higher than those in the uninfected group,and the BMI was less than that in the uninfected group,and the difference was statistically significant( P<0. 05).The specimens were examined 140 times,a total of 8 types,25 strains of pathogenic bacteria were isolated and cultured,the positive rate was 17. 86%.9 strains of G+bacteria,accounting for 36%; 16 strains of G-bacteria,accounting for 64%,of which the most common pathogenic bacteria infection was Salmonella Shigella infection,and G-bacteria infection was more common.Most of the nosocomial infections( 71. 43%) were the first infection,and the upper respiratory tract infection( 45. 71%) was the most common; Patients with schizophrenia had the highest proportion of nosocomial infection( 62. 86%),and winter( 41. 43%) was the season of high incidence of infection.Multivariate analysis showed that age and length of hospital stay were independent influencing factors for nosocomial infection in elderly patients with mental illness( P<0. 05).Conclusion The main pathogenic bacteria causing nosocomial infections in elderly patients with mental illness are gram negative bacteria,mainly respiratory tract infection,and the length of stay and age are closely related to the occurrence of nosocomial infection
Key words:  elderly  mentalillness  nosocomialinfection  pathogenicbacteria  clinicalcharacteristics
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